Ace Hemostasis Coagulation Quiz 2026 – Unleash Your Inner Clotting Pro!

In acute DIC, widespread activation of coagulation consumes platelets and coagulation factors, especially fibrinogen, so levels of fibrinogen fall. This consumption of fibrinogen, or hypofibrinogenemia, is a hallmark of acute DIC. You wouldn’t expect thrombocytosis; platelets are used up, leading to low platelets. D-dimer would be elevated due to increased fibrin formation and breakdown, not negative. Thrombin time is typically prolonged in this setting because low fibrinogen and fibrin degradation products interfere with clot formation, not shortened.